Table 1.

Payer information needs

Well-designed, well-conducted studies demonstrating impact of PGx testing on: clinical outcomes (effectiveness; safety) economic outcomes (direct and indirect costs; budget impact) Studies comparing PGx testing to usual care (prospective; ideally randomized controlled trials) Studies conducted in real-world populations Studies published in peer-reviewed literature Algorithms or clinical practice guidelines to guide appropriate use of test in clinical practice including need for informed consent, referral for genetic counseling Education for clinicians and patients

Semi-structured interviews conducted with 9 payers and 8 health care delivery organizations [see reference 56].