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Temporal pattern of expression of putative downstream genes of Sox8 in adult testes. Quantitative RT-PCR determined the relative abundance of Pde4D, Cep27, Cldn3, Cldn23, and Cd164 transcripts compared to Gapdh mRNA in heterozygous (black bars) and homozygous (gray bars) mutant testes for Sox8 at 2 months (A), 3 months (B) and 5 months (C) after birth. The data are expressed as mean ± SEM.
