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Protein sequence alignment of the human Gi/o family. Gly2/Ser6 motif for myristoylation and Cys3 for palmitoylation (bold), GTP-binding motif (GAGESGKS), Mg2+ -binding domain (DVGG), guanine ring-binding motif (NKKD), cysteine (∗) (at −4 from carboxyl terminal) for PTX ADP ribosylation on Gi/o proteins. Ggust is gustducin α subunit (gnat3). Gt sequence from cone transducin. Percentage of identity/homology. Spaces for alignment.
