Table 3.

Association of ESR1 haplotypes with hip fractures in women.

	Frequency in cases (%)	Frequency in controls (%)	OR (95% CI)	p-value
2-SNP
CG	23.6	20.1	1	-
TG	0.8	1.2	0.54 (0.26-1.16)	0.22
CA	3.0	6.5	0.39 (0.26-0.59)	1.8 × 10-5
TA	72.6	72.2	0.85 (0.70-1.0)	0.77
3-SNP
GCG	14.7	13.5	1	-
CCG	8.9	6.8	1.18 (0.83-1.69)	0.05
CTG	0.8	1.2	0.58 (0.27-1.25)	0.22
GCA	0.6	3.2	0.17 (0.08-0.37)	8.6 × 10-7
CCA	2.4	3.3	0.67 (0.4-1.13)	0.13
GTA	1.4	1.9	0.65 (0.32-1.31)	0.26
CTA	71.2	70.1	0.92 (0.73-1.17)	0.52

2-SNP haplotypes include rs3020314 and rs1884051

3-SNP haplotypes include rs1801132, rs3020314 and rs1884051