Table 2.
Haplotypes and phased genotypes distributions for the rs25531 and 5-HTTLPR polymorphisms in the SLC6A4 gene in control and NS-MD populations.
| AP2, 5-HTTLPR | Controls | MR patients | MR vs Controls | |
|---|---|---|---|---|
| χ2 | p | |||
| Haplotypes (5HTT gene) | ||||
| AL | 179 (54.57) | 110 (56,12) | 0.12 | 0.73 |
| AS, GL, GS | 149 (45.43) | 86 (43,88) | ||
| Phased genotypes (5HTT gene) | ||||
| AL/AL | 45 (27.44) | 28 (28.57) | 1.28 | 0.73 |
| AL/AS | 73 (44.51) | 47 (47.96) | ||
| AL/GL | 16 (9.76) | 6 (6.12) | ||
| AL/GS | 0 (0.0) | 1 (1.02) | ||
| Others | 30 (18.29) | 16 (16.33) | ||
| Genotypes (5HTT/BDNF genes) | ||||
| AL AL/Val Val | 19 (13.00) | 10 (12.66) | 0.65 | 0.88 |
| AL AL/Val Met | 21 (14.40) | 11 (13.92) | ||
| Others/Val Val | 59 (40.40) | 36 (45.57) | ||
| Others/Val Met | 47 (32.20) | 22 (27.85) | ||