Table 1.
Distribution of caspase-1 polymorphisms in patients and controls
| Caspase-1 polymorphisms | Patients | Controls |
|---|---|---|
| rs501192 (intron 6) | ||
| GG | 436 (0.72) | 519 (0.73) |
| GA | 151 (0.25) | 175 (0.25) |
| AA | 18 (0.03) | 15 (0.02) |
| Total | 605 | 709 |
| Allele frequency G/A | 0.84/0.16 | 0.85/0.15 |
| rs556205 (intron 7) | ||
| AA | 514 (0.82) | 606 (0.84) |
| AC | 109 (0.17) | 113 (0.16) |
| CC | 5 (0.01) | 3 (0.00) |
| Total | 628 | 722 |
| Allele frequency A/C | 0.90/0.10 | 0.92/0.08 |
| rs530537 (intron 7) | ||
| AA | 159 (0.26) | 200 (0.28) |
| AG | 313 (0.52) | 374 (0.52) |
| GG | 134 (0.22) | 144 (0.20) |
| Total | 606 | 718 |
| Allele frequency A/G | 0.52/0.48 | 0.54/0.46 |
Figures in parentheses indicate frequencies; p-values > 0.05 for all allelic and genotypic comparisons