Table 3.
Summary of results for free energy measurements obtained with EVAL-FE methods.
| Method | Statistics | MFE_AD [kcal/mol] | Pearson coeff. (r) | RMSE |
|---|---|---|---|---|
| MultiRNAFold | min | 0.0000 | 0.7352 | 4.418 |
| (Mathews) | q1 | 0.300 | ||
| median | 0.800 | |||
| mean | 2.672 | |||
| q3 | 3.395 | |||
| max | 18.400 | |||
| stddev | 3.521 | |||
| MultiRNAFold | min | 0.0000 | 0.7456 | 4.223 |
| (SantaLucia) | q1 | 0.330 | ||
| median | 0.680 | |||
| mean | 2.553 | |||
| q3 | 3.390 | |||
| max | 17.200 | |||
| stddev | 3.367 | |||
| min | 0.0000 | 0.7434 | 4.101 | |
| q1 | 0.2528 | |||
| median | 0.6128 | |||
| UNAFold | mean | 2.4110 | ||
| q3 | 2.9970 | |||
| max | 13.0000 | |||
| stddev | 3.319 | |||
| Vienna | min | 0.0000 | 0.7413 | 3.876 |
| Package | q1 | 1.820 | ||
| median | 2.440 | |||
| mean | 3.167 | |||
| q3 | 3.965 | |||
| max | 15.400 | |||
| stddev | 2.236 |
Summary of results for free energy measurements obtained with EVAL-FE methods. The p-values for the Pearson correlation test were less than 2.2e-16 in all cases.