Table 3.
Concentrations of GSH, GSSG, and total glutathione (GSH + GSSG) in mitochondria of SAM mice fed with Diet I
Tissue | GSH (nmol/mg protein) |
GSSG (nmol/mg protein) |
GSH + GSSG (nmol/mg protein) |
Total glutathione (% change) |
---|---|---|---|---|
Liver | ||||
Control | 7.17 ± 0.48 | 0.176 ± 0.025 | 7.25 ± 0.50 | |
Diet I | 7.21 ± 0.24 | 0.182 ± 0.027 | 7.40 ± 0.27 | NSa |
Kidney | ||||
Control | 1.79 ± 0.15 | 0.008 ± 0.002 | 1.80 ± 0.15 | |
Diet I | 1.88 ± 0.27 | 0.010 ± 0.002 | 1.89 ± 0.27 | NS |
Heart | ||||
Control | 4.54 ± 0.33 | 0.298 ± 0.039 | 4.84 ± 0.37 | |
Diet I | 4.03 ± 0.45 | 0.281 ± 0.052 | 4.31 ± 0.52 | NS |
Brain | ||||
Control | 4.22 ± 0.25 | 0.031 ± 0.005 | 4.25 ± 0.25 | |
Diet I | 4.29 ± 0.23 | 0.031 ± 0.004 | 4.32 ± 0.23 | NS |
Skeletal muscle | ||||
Control | 1.12 ± 0.09 | 0.102 ± 0.012 | 1.22 ± 0.10 | |
Diet I | 1.12 ± 0.10 | 0.040 ± 0.007b | 1.16S ± 0.11 | NS |
NS, not significant.
Significant difference (P < 0.05) between control (n = 5) and experimental (n = 4) mice.