Table 2.
Liver disease mortality by alcohol consumption
| Units of alcohol consumed per week | P | RR per unit increase* | ||||||
|---|---|---|---|---|---|---|---|---|
| 0 (n=3355) | 1-7 (n=1817) | 8-14 (n=1766) | 15-21 (n=1017) | 22-34 (n=942) | ≥35 (n=662) | |||
| Liver disease as main cause of death† | ||||||||
| Deaths | 10 | 9 | 7 | 16 | 19 | 19 | – | – |
| RR1 | 1 | 1.62 (0.65 to 3.99) |
1.33 (0.51 to 3.51) |
5.61 (2.54 to 12.4) |
7.35 (3.40 to 15.9) |
11.5 (5.31 to 25.0) |
<0.0001 | 1.03 (1.02 to 1.03) |
| RR2 | 1 | 1.50 (0.60 to 3.70) |
1.24 (0.47 to 3.27) |
5.17 (2.32 to 11.5) |
6.81 (3.10 to 14.9) |
10.5 (4.74 to 23.3) |
<0.0001 | 1.03 (1.02 to 1.03) |
| Liver disease in any position‡ | ||||||||
| Deaths | 19 | 18 | 22 | 23 | 33 | 31 | – | – |
| RR1 | 1 | 1.66 (0.87 to 3.17) |
2.17 (1.17 to 4.01) |
4.22 (2.29 to 7.76) |
6.56 (3.72 to 11.6) |
9.58 (5.38 to 17.1) |
<0.0001 | 1.02 (1.02 to 1.03) |
| RR2 | 1 | 1.59 (0.83 to 3.03) |
2.04 (1.10 to 3.78) |
3.75 (2.03 to 6.95) |
5.90 (3.31 to 10.5) |
8.40 (4.64 to 15.2) |
<0.0001 | 1.02 (1.01 to 1.03) |
RR=relative rate (95% CI), RR1= relative rate adjusted for age and study, RR2= relative rate adjusted for age, study, social class, smoking, height, bronchitis, FEV1, angina, ischaemia on electrocardiogram, and diabetes.
*Excluding non-drinkers.
†P for interaction between studies=0.93.
‡P for interaction between studies=0.87.