Figure 3.

FcγR^-/- mice alter chemokines and cytokines expression in the lungs during SR-induced HP. The transcription of chemokines such as IP-10, Mip-1α, RANTES and MCP-1 (A) and cytokines, IFN-γ, and IL-4 (B) were measured using real-time PCR in the lungs from B6 and FcγR^-/- mice 7 days after the first administration of SR antigen. All expression levels were normalized to GAPDH. The results shown are representative of three independent experiments and statistical analysis was performed using the program Prism 4.0 (n=3, ^*p<0.05, B6 mice versus FcγR^-/- mice).