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. Author manuscript; available in PMC: 2010 Mar 12.
Published in final edited form as: Free Radic Biol Med. 2008 Aug 3;45(9):1232–1242. doi: 10.1016/j.freeradbiomed.2008.07.022

Fig. 3.

Fig. 3

Bz-423 activates Bak and Bax. (A) MEFs were pre-treated with MnTBAP (100 μM) or vitamin E (100 μM) for 30 min prior to treatment with Bz-423 (12 μM, 12 h) and cell fractionation. Cytosolic or mitochondrial Bax was detected by immunoblot. The black vertical line indicates where non-adjacent lanes from the same gel were used to compile this figure. (B) MEFs were treated with vehicle or Bz-423 (12 μM, 12 h) followed by detection of activated N-terminal Bax or Bak by imunofluorescence microscopy.

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