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. Author manuscript; available in PMC: 2011 Mar 5.
Published in final edited form as: Cell Stem Cell. 2010 Mar 5;6(3):265–278. doi: 10.1016/j.stem.2010.02.002

Figure 2.

Figure 2

Repopulation kinetics of transplanted SP subtypes.

(A) Competitive transplant scheme for lower- and upper-SPKLS cells individually (200 per recipient) or in combination (100 of each subtype per recipient), with 200,000 whole bone marrow competitor cells in all transplants. (B) Overall peripheral blood contribution (Engraft) and proportional contribution to myeloid, B- and T-cells at 4- and 16-weeks after transplantation of SP fractions into separate mice. (C) Peripheral blood analysis after transplantation of both upper- and lower-SP into the same recipients. (D) Scheme for re-purification of primary HSCs and transplantation into secondary recipients. (E) Contribution to the blood of SP sub-populations after secondary transplantation at 4- and 16-weeks. (F) Reconstitution of blood in secondary recipients by SP originally co-transplanted in primary transplants (see also Figure S2A).