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. Author manuscript; available in PMC: 2011 Mar 5.
Published in final edited form as: Cell Stem Cell. 2010 Mar 5;6(3):265–278. doi: 10.1016/j.stem.2010.02.002

Figure 5.

Figure 5

Aging SP subtypes retain lineage-differentiation biases.

(A) Contour plot comparisons of young (10-week old) and old (90-week old) SPs showing an accumulation of lower-SP cells in aged mice. (B) Overall peripheral blood contribution (Engraft) and proportional contribution to myeloid, B- and T-cells at 4- and 16-weeks after transplantation of old and young SP fractions. (C) Peripheral blood contribution after secondary transplantation from recipients of aged lower- and upper-SPKLS cells.