Figure 3.

Skin graft survival when the allograft lacks surface expression of MHC class I or II molecules. Eight- to 12-week-old BALB/c IL-2Rβ^−/− mice that were adoptively treated with the indicated population of Treg cells at birth (denoted as the donor Treg strain→IL-2Rβ^−/− recipient strain) received skin grafts from BALB/c, C3H, and B6 MHC-deficient mice. (A) Tolerance to B6 MHC class II–deficient (B6 II^−/−) skin. (B) Tolerance to MHC class I–deficient (B6 β₂m^−/−) skin. The number of mice/group from a single experiment and the MST of allogeneic skin grafts are listed within each panel of the figure.