TABLE 2.
Joinpoint Analyses Showing APC in Breast Cancer Incidence Among Women Aged 50 Years and Older With Known ER Status, by County Median Household Income, Race/Ethnicity, and Age at Diagnosis: US SEER 13 Registries Database, 1992–2005
| County Median Household Income | Segment 1, APC (95% CI) | Segment 2 |
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| ER Status | Race/Ethnicity | Joinpoint (95% CI) | APC (95% CI) | ||
| Aged 50–69 y | |||||
| ER positive | All women | Low | 4.1 (2.1, 6.2) | 1999 (1996, 2002) | −0.7 (−2.8, 1.5) |
| ER positive | All women | High | 4.9 (3.0, 6.9) | 1999 (1998, 2002) | −2.5 (−4.3, −0.5) |
| ER positive | White, non-Hispanic | Low | 4.6 (2.3, 6.9) | 1999 (1996, 2002) | −1.5 (−4.0, 1.1) |
| ER positive | White, non-Hispanic | High | 4.6 (2.9, 6.3) | 2000 (1998, 2002) | −3.7 (−6.5, −0.9) |
| ER positive | Black, non-Hispanic | Low | 2.5 (1.5, 3.5) | ||
| ER positive | Black, non-Hispanic | High | 1.6 (0.1, 3.0) | ||
| ER positive | API, non-Hispanic | Low | 5.1 (3.4, 6.8) | ||
| ER positive | API, non-Hispanic | High | 4.6 (2.0, 7.3) | 1999 (1997, 2002) | −2.3 (−4.8, 0.3) |
| ER positive | Hispanic | Low | 3.6 (2.4, 4.8) | ||
| ER positive | Hispanic | High | 1.5 (0.4, 2.7) | ||
| ER negative | All women | Low | 0.7 (−0.1, 1.5) | ||
| ER negative | All women | High | −0.2 (−0.8, 0.3) | ||
| ER negative | White, non-Hispanic | Low | 0.1 (−0.7, 1.0) | ||
| ER negative | White, non-Hispanic | High | −0.4 (−1.1, 0.3) | ||
| ER negative | Black, non-Hispanic | Low | 2.1 (0.3, 3.9) | ||
| ER negative | Black, non-Hispanic | High | 1.2 (0.0, 2.5) | ||
| ER negative | API, non-Hispanic | Low | 1.9 (−0.5, 4.3) | ||
| ER negative | API, non-Hispanic | High | −0.9 (−2.2, 0.3) | ||
| ER negative | Hispanic | Low | 3.0 (1.0, 5.0) | ||
| ER negative | Hispanic | High | 0.2 (−1.1, 1.5) | ||
| Aged ≥ 70 y | |||||
| ER positivea | All women | Low | −2.8 (−18.1, 15.4) | 1994 (1994, 2000) | 6.8 (−9.4, 25.8) |
| ER positivea | All women | High | 1.4 (0.1, 2.7) | 1996 (1994, 1997) | 5.1 (1.3, 9.1) |
| ER positive | White, non-Hispanic | Low | 4.0 (1.2, 6.8) | 1998 (1996, 2001) | −0.8 (−2.9, 1.2) |
| ER positivea | White, non-Hispanic | High | 1.5 (0.2, 2.9) | 1996 (1994, 1997) | 5.5 (1.5, 9.7) |
| ER positive | Black, non-Hispanic | Low | 3.3 (2.1, 4.6) | ||
| ER positive | Black, non-Hispanic | High | 2.4 (1.0, 3.8) | ||
| ER positive | API, non-Hispanic | Low | 3.8 (1.5, 6.5) | ||
| ER positive | API, non-Hispanic | High | 0.7 (−0.8, 2.3) | ||
| ER positive | Hispanic | Low | 1.8 (0.6, 3.1) | ||
| ER positive | Hispanic | High | 1.9 (0.4, 3.5) | ||
| ER negative | All women | Low | 0.5 (−0.5, 1.6) | ||
| ER negative | All women | High | 0.5 (−0.2, 1.2) | ||
| ER negative | White, non-Hispanic | Low | 0.5 (−0.6, 1.2) | ||
| ER negative | White, non-Hispanic | High | 0.4 (−0.4, 1.2) | ||
| ER negative | Black, non-Hispanic | Low | 3.8 (1.9, 5.8) | ||
| ER negative | Black, non-Hispanic | High | 1.9 (−0.3, 4.2) | ||
| ER negative | API, non-Hispanic | Low | 2.2 (−2.0, 6.5) | ||
| ER negative | API, non-Hispanic | High | −0.9 (−3.2, 1.5) | ||
| ER negative | Hispanic | Low | −0.9 (−3.3, 1.6) | ||
| ER negative | Hispanic | High | 6.0 (2.4, 9.7) | ||
Note. API = Asian/Pacific Islander; APC = annual percentage change; ER = estrogen receptor; SEER = Surveillance, Epidemiology and End Result; CI = confidence interval.
Additional segments: joinpoint (95% CI) and APC (95% CI): age ≥ 70: (1) all women, low-income county, ER+: segment 3 joinpoint = 1997 (1997, 2003), APC = −0.8 (−2.4, 0.0.9); (2) all women, high-income county, ER+: segment 3 joinpoint = 1999 (1997, 2000), APC = −2.8 (−4.6, −1.0), and segment 4 joinpoint = 2003 (2000, 2003), APC = 2.6 (−1.1, 6.4); (3) White non-Hispanic, high-income county, ER+: segment 3 joinpoint = 1999 (1997, 2000), APC = −2.6 (−4.5, −0.8), and segment 4 joinpoint = 2003 (2000, 2003), APC = 3.0 (−0.9, 7.2).