Table 2. Relation of Reward-Related Striatal and Rostral Medial Prefrontal Activation to Adolescents' Subjective Positive Affect in Natural Settings and Depressive Symptoms.

Region	Hemisphere	Talairach coordinates of maximum voxel in cluster			Cluster Size	t	pFDR <
		x	y	z
Subjective Positive Affect
Reward Anticipation – Positive Correlation
Thalamus/Caudate	R	8	-9	13	238	3.34	0.05
Reward Outcome – Positive Correlation
Thalamus/Caudate	R	10	-2	10	693	2.94	0.05
Depressive Symptoms
Reward Anticipation – Positive Correlation
Medial Frontal Gyrus, BA10	R	6	62	1	91	3.45	0.05
Anterior Cingulate, BA32	L	-6	19	27	82	2.45	0.05
Reward Outcome – Negative Correlation
Ventral Striatum	L	-14	2	-7	402	3.09	0.05

Note: Results are from regressions focusing on the striatum and the rostral medial prefrontal cortex. df=75 for subjective positive affect and 74 for depressive symptoms. For clusters labeled Thalamus/Caudate, the maximum voxel for the cluster was located in the thalamus, but most of the cluster was located in the caudate. BA: Brodmann Area. FDR: False discovery rate-corrected. When excluding cases with depressive symptoms >30, the correlations with BA32 during reward anticipation (63 voxels, [-4,34,4], t=2.69, p<.005) and striatum during reward outcome (caudate: 103 voxels, [-2,12,6], t=2.95, p<.005) remained significant.