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. 2010 Feb 16;102(4):693–703. doi: 10.1038/sj.bjc.6605534

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Copyright © 2010 Cancer Research UK

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FISH analysis. Chromosome metaphase spreads were hybridised with FISH probes for (A) chromosome 12p (red) and (B) chromosome 12q (green) to confirm probe specificity and FISH analysis performed as described in Materials and Methods. Representative colorectal tumour sections (C) without and (D) with a K-Ras gene amplification are illustrated.