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. 2010 Jan 19;102(4):748–753. doi: 10.1038/sj.bjc.6605526

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Copyright © 2010 Cancer Research UK

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Anti-AFP CD4 T-cell responses are only detected in HCC patients. (A) Peptide-specific intracellular IFN-γ production by CD4 and CD8 T cells was determined using flow cytometry. Representatives of CD4 and CD8 T-cell responses against AFP-derived peptides are shown. (B) The percentages of HCC patients or controls with CD4 or/and CD8 T cells reacting to AFP-derived peptides are shown. (C) The number of HCC patients with or without anti-AFP CD4, CD8 and CD4 and CD8 T-cell responses is presented.