Table 2.

Overview of results of multivariate analysis (PLS-DA) of various data sets.

	Original data set		After variable selection
	# variables	error rate	# variables	error rate
plasma proteomics	66	21%	46	10%
plasma oxylipids	30	26%	19	10.5%
plasma GC-MS	137	42%	-	-
plasma LC-MS polar	130	53%
plasma LC-MS lipids	61	37%	-	-
plasma LC-MS free fatty acids	14	37%	-	-
PBMC transcriptomics	-	-	3355	0%

All data sets were analyzed for differences between diclofenac and placebo treatment by PLS-DA. The results of the different multivariate models are expressed as error rates. Only when the error rate for the original data set was < = 30%, analysis was continued by variable selection, as described in the materials and methods section.