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Fibrinogen-treatment induces MMP-9 secretion from human monocytes. Human monocytes were exposed to different concentrations of fibrinogen and MMP-9 levels were measured in the supernatants (A) and intra-cellularly (B). In the supernatants of the fibrinogen-treated cells, MMP-9 levels were 15 times higher than in un-treated monocytes were measured. Intracellular MMP-9 levels did not increase twice the concentration of untreated cells. Results are given as mean ± SEM, n = 3.*: p < 0.05.
