Table 2.
Mean AHV-1 gC copies and viral loads in different samples for practical applications
| Samples (lg copies/g) |
Groups | 1 h | 4 h | 8 h | 12 h | 1 d | 3 d | 5 d | 7 d | 2 wk | 4 wk |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Liver | 1 | 9.38 ± 0.23 | 9.15 ± 0.15 | 8.93 ± 0.18 | 8.62 ± 0.09 | 8.41 ± 0.19 | 8.18 ± 0.08 | 8.06 ± 0.20 | 8.03 ± 0.12 | 8.03 ± 0.25 | 7.98 ± 0.14 |
| 2 | 8.45 ± 0.01 | 8.62 ± 0.13 | 8.58 ± 0.08 | 8.37 ± 0.07 | 8.23 ± 0.10 | 7.95 ± 0.19 | 7.72 ± 0.16 | 7.57 ± 0.16 | 7.28 ± 0.14 | 6.87 ± 0.19 | |
| Pancreas | 1 | 8.32 ± 0.03 | 8.21 ± 0.07 | 8.13 ± 0.04 | 8.01 ± 0.12 | 7.95 ± 0.09 | 7.87 ± 0.05 | 7.73 ± 0.17 | 7.56 ± 0.07 | 7.42 ± 0.15 | 7.35 ± 0.05 |
| 2 | 8.16 ± 0.16 | 8.38 ± 0.10 | 8.22 ± 0.14 | 8.08 ± 0.08 | 8.00 ± 0.11 | 7.98 ± 0.06 | 7.86 ± 0.14 | 7.61 ± 0.18 | 7.2 ± 0.03 | 6.69 ± 0.05 | |
| Spleen | 1 | 9.23 ± 0.11 | 9.06 ± 0.06 | 8.75 ± 0.10 | 8.52 ± 0.04 | 8.32 ± 0.16 | 8.26 ± 0.14 | 8.15 ± 0.18 | 8.12 ± 0.24 | 7.94 ± 0.08 | 7.87 ± 0.17 |
| 2 | 9.26 ± 0.08 | 9.49 ± 0.06 | 9.21 ± 0.13 | 8.92 ± 0.16 | 8.75 ± 0.20 | 8.51 ± 0.13 | 8.33 ± 0.07 | 8.07 ± 0.81 | 7.68 ± 0.13 | 7.53 ± 0.12 | |
| Kidney | 1 | 8.47 ± 0.02 | 8.36 ± 0.05 | 8.24 ± 0.14 | 8.13 ± 0.13 | 7.94 ± 0.11 | 7.62 ± 0.05 | 7.48 ± 0.18 | 7.31 ± 0.27 | 7.33 ± 0.13 | 7.29 ± 0.11 |
| 2 | 8.41 ± 0.13 | 8.33 ± 0.17 | 8.23 ± 0.08 | 8.05 ± 0.15 | 7.97 ± 0.04 | 7.82 ± 0.09 | 7.79 ± 0.11 | 7.58 ± 0.14 | 6.96 ± 0.12 | 6.84 ± 0.06 | |
| Lung | 1 | 8.89 ± 0.07 | 8.77 ± 0.10 | 8.44 ± 0.14 | 8.14 ± 0.11 | 8.02 ± 0.05 | 7.88 ± 0.18 | 7.51 ± 0.21 | 7.50 ± 0.16 | 7.42 ± 0.11 | 7.30 ± 0.16 |
| 2 | 8.34 ± 0.03 | 8.58 ± 0.03 | 8.42 ± 0.17 | 8.21 ± 0.04 | 8.14 ± 0.16 | 7.86 ± 0.13 | 7.82 ± 0.18 | 7.62 ± 0.21 | 7.35 ± 0.21 | 7.11 ± 0.15 | |
| Thymus | 1 | 9.2 ± 0.16 | 9.04 ± 0.11 | 8.86 ± 0.18 | 8.52 ± 0.05 | 8.4 ± 0.19 | 8.23 ± 0.15 | 8.11 ± 0.17 | 8.03 ± 0.01 | 7.95 ± 0.05 | 7.84 ± 0.08 |
| 2 | 9.27 ± 0.14 | 9.41 ± 0.18 | 9.22 ± 0.06 | 8.94 ± 0.20 | 8.72 ± 0.13 | 8.38 ± 0.07 | 8.04 ± 0.17 | 7.77 ± 0.05 | 7.56 ± 0.14 | 7.39 ± 0.15 | |
| Heart | 1 | 8.68 ± 0.07 | 8.59 ± 0.14 | 8.44 ± 0.17 | 8.20 ± 0.03 | 8.13 ± 0.02 | 8.07 ± 0.13 | 8.02 ± 0.25 | 7.94 ± 0.17 | 7.82 ± 0.22 | 7.76 ± 0.14 |
| 2 | 9.06 ± 0.05 | 9.14 ± 0.16 | 9.08 ± 0.16 | 8.95 ± 0.14 | 8.63 ± 0.11 | 8.34 ± 0.18 | 8.12 ± 0.06 | 7.71 ± 0.11 | 7.52 ± 0.21 | 7.23 ± 0.12 | |
| Brain | 1 | 8.25 ± 0.09 | 8.04 ± 0.07 | 7.83 ± 0.18 | 7.77 ± 0.16 | 7.71 ± 0.12 | 7.67 ± 0.04 | 7.64 ± 0.09 | 7.48 ± 0.13 | 7.39 ± 0.15 | 7.24 ± 0.07 |
| 2 | 9.05 ± 0.11 | 9.18 ± 0.13 | 9.02 ± 0.05 | 8.93 ± 0.08 | 8.64 ± 0.02 | 8.36 ± 0.05 | 7.84 ± 0.10 | 7.57 ± 0.16 | 7.33 ± 0.19 | 7.14 ± 0.18 | |
| Duodenum | 1 | 8.77 ± 0.02 | 8.59 ± 0.07 | 8.29 ± 0.23 | 8.05 ± 0.11 | 7.94 ± 0.13 | 7.85 ± 0.07 | 7.81 ± 0.21 | 7.78 ± 0.27 | 7.63 ± 0.20 | 7.61 ± 0.19 |
| 2 | 8.25 ± 0.16 | 8.33 ± 0.03 | 8.23 ± 0.07 | 8.16 ± 0.09 | 8.04 ± 0.02 | 7.69 ± 0.15 | 7.41 ± 0.19 | 7.26 ± 0.16 | 6.81 ± 0.09 | 6.64 ± 0.11 | |
| Rectum | 1 | 8.68 ± 0.07 | 8.47 ± 0.16 | 8.26 ± 0.10 | 7.98 ± 0.23 | 7.94 ± 0.23 | 7.88 ± 0.17 | 7.91 ± 0.27 | 7.83 ± 0.14 | 7.74 ± 0.03 | 7.70 ± 0.18 |
| 2 | 8.23 ± 0.05 | 8.27 ± 0.08 | 8.18 ± 0.11 | 8.12 ± 0.05 | 8.02 ± 0.10 | 7.78 ± 0.17 | 7.52 ± 0.15 | 7.21 ± 0.06 | 6.95 ± 0.09 | 6.78 ± 0.05 | |
| Harderian gland | 1 | 8.32 ± 0.08 | 8.11 ± 0.04 | 7.94 ± 0.21 | 7.72 ± 0.14 | 7.62 ± 0.09 | 7.54 ± 0.24 | 7.5 ± 0.08 | 7.38 ± 0.22 | 7.41 ± 0.29 | 7.33 ± 0.19 |
| 2 | 8.23 ± 0.15 | 8.35 ± 0.07 | 8.21 ± 0.11 | 8.13 ± 0.14 | 8.05 ± 0.19 | 7.77 ± 0.14 | 7.52 ± 0.07 | 7.18 ± 0.20 | 6.55 ± 0.01 | 6.39 ± 0.04 | |
| Bursa of Fabricius | 1 | 8.86 ± 0.07 | 8.80 ± 0.05 | 8.50 ± 0.10 | 8.17 ± 0.09 | 8.02 ± 0.17 | 7.85 ± 0.19 | 7.78 ± 0.11 | 7.72 ± 0.09 | 7.6 ± 0.22 | 7.63 ± 0.25 |
| 2 | 8.83 ± 0.11 | 8.92 ± 0.13 | 8.88 ± 0.07 | 8.79 ± 0.17 | 8.44 ± 0.19 | 8.25 ± 0.15 | 7.88 ± 0.19 | 7.47 ± 0.10 | 6.68 ± 0.08 | 6.53 ± 0.13 |
Group 1: pcDNA3.1-gC
Group 2: AHV-1 Cha strain vaccine