Figure 1.

Alignment of PAS domain amino acid sequences of vertebrate AHRs and a possible invertebrate AHR homolog. Deduced amino acid sequences in the PAS domains of vertebrate AHRs and C. elegans C41G7.5 were aligned by using clustalw(1.6). GenBank accession numbers are listed in Table 2. Amino acids that are identical in five or more of the sequences are boxed and shaded. Similar amino acids are in boldface type. The PAS “A” and “B” imperfect repeats (as defined originally in refs. 15 and 18) are underlined. The consensus sequence (≥50%) is shown below the aligned sequences.