Figure 5. Functional residues at the RNA binding site.

A) Structural alignment of C alpha traces of DDX3X and DDX4. B) RNA binding region of DDX3X structurally alignment with DDX4 (RMSD = 0.4). C) Plot of normalized C alpha displacements with conservation scores to identify flexibility of functional residues at this region. D) Flexible (green) and rigid (yellow) functional residues identified at the RNA binding region of DDX3X.