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. 2010 Mar 15;5(3):e9668. doi: 10.1371/journal.pone.0009668

Table 4. Segregation analysis of oesophageal cancer in the Taihang general population with type influences age of onset and sex-dependence.

Parametera Dominant Recessive Codominant Descending Polygenic No major type Environmental General
qA 0.355 0.644 0.481 0.352 0.486 - 0.486 0.859
τAA 1.0 1.0 1.0 1.0 - - 0.486 0.49
τAB 0.5 0.5 0.5 0.5 - - 0.486 0.48
τBB 0 0 0 0 - - 0.486 0
βAAM −12.729 −12.729 −13.194 −12.729 −14.827 −10.770 −14.827 −12.980
βABM −12.729 −15.785 −17.472 −15.785 −18.463 −10.770 −18.463 −16.017
βBBM −15.785 −15.785 −14.774 −15.785 −22.293 −10.770 −22.294 −22.071
βAAF −13.540 −13.540 −14.109 −13.540 −15.822 −11.424 −15.822 −13.565
βABF −13.540 −16.596 −18.387 −16.596 −19.458 −11.424 −19.458 −16.602
βBBF −16.596 −16.596 −15.689 −16.596 −23.288 −11.424 −23.289 −22.656
α 0.210 0.21 0.224 0.21 0.259 0.155 0.259 0.219
γ 0b 0 b 0.100 0 b 0.216 0.018 0.216 0.859
χ2 364.85 364.88 349.79 364.82 340.02 405.04 340.02
df 3 3 2 2 3 5 2
P value 9.07E-79 8.94E-79 1.11E-76 6.03E-80 2.16E-73 2.43E-85 1.46E-74
-2lnL 7907.39 7907.42 7892.33 7907.36 7882.56 7947.58 7882.56 7542.54
AIC 7921.39 7921.42 7908.33 7923.36 7896.56 7957.58 7898.56 7562.54

-: Parameter at this value is not estimated.

a: See Materials and Methods for definitions of the parameters.

b: Parameter estimate went to bound.