Table 1. Performance of different SVM classifiers in LOO CV.

Model	C	γ	Th	SN	SP	Accuracy	MCC
AAC	19	0.001	−0.9	80.00	84.45	83.65	0.557
DPC	2	0.01	−0.7	80.00	84.45	83.65	0.557
CC	0	4	−1.0	64.00	75.65	73.55	0.328
HC	0	0.1	−1.0	68.00	74.48	73.31	0.346
MPC	2	0.001	−1.0	77.33	76.53	76.68	0.439
ACM	0	0.00001	−1.0	80.00	78.29	78.60	0.479
ACHM	20	0.001	−0.8	82.66	86.80	86.05	0.610
PSSM-a	22	4	−0.6	80.00	87.68	86.29	0.604
PSSM-b	60	0.0001	−0.6	82.66	81.81	81.97	0.541

Th–Threshold, SN–sensitivity, SP–specificity, MCC–Matthews Correlation Coefficient.