Table 5.
Association between health-related variables and ART adherence
| VAS adherence (≥ 95%) | Dose, schedule and food adherence | ||||||||
|---|---|---|---|---|---|---|---|---|---|
|
N (%) 519 |
Crude OR (95% CI) |
P |
Adjusted ORa, b (95% CI) |
P |
Crude OR (95% CI) |
P |
Adjusted ORa, c (95% CI) |
P | |
| Time since diagnosis | |||||||||
| 2006-1995 | 125 (24.8) | 1.00 | 1.00 | ||||||
| 2007/8 | 379 (75.2) | 0.49 (0.26-0.92) | .026 | ... | 0.80 (0.50-1.26) | .330 | --- | ||
| Hospital admission in the past 6 months | |||||||||
| No | 463 (89.7) | 1.00 | 1.00 | ||||||
| Yes | 53 (10.3) | 1.51 (0.62-3.69) | .326 | ... | 0.98 (0.51-1.85) | .937 | --- | ||
| CD4 count | |||||||||
| ≤ 200 | 420 (83.2) | 1.00 | ... | 1.00 | 1.00 | ||||
| >200 | 85 (16.8) | 1.19 (0.63-2.26) | .599 | 2.90 (1.52-5.53) | .001 | 3.32 (1.18-9.38) | .023 | ||
| HIV symptoms (range 0-20) | |||||||||
| M (SD) | 1.2 (2.6) | 1.08 (0.96-1.21) | .213 | ... | 1.06 (0.97-1.15) | .199 | --- | ||
| Overall Quality of Lifed | |||||||||
| M (SD) | 4.3 (0.7) | 2.87 (2.00-4.10) | .000 | 0.94 (0.52-1.68) | .830 | 3.91 (2.71-5.65) | .000 | 2.06 (1.07-3.98) | .031 |
| General health perceptionsd | |||||||||
| M (SD) | 4.4 (0.7) | 2.69 (1.95-3.73) | .000 | 1.72 (1.01-2.95) | .047 | 3.72 (2.62-5.28) | .000 | 1.57 (0.89-2.79) | .121 |
| WHOQOL-HIV BREFscores | |||||||||
| Physical domaine | 15.6 (2.7) | 1.35 (1.22-1.49) | .000 | 0.94 (0.78-1.13) | .512 | 1.54 (1.40-1.69) | .000 | 0.87 (0.70-1.08) | .201 |
| Psychological domaine | 14.6 (3.2) | 1.40 (1.28-1.53) | .000 | 1.17 (0.97-1.41) | .099 | 1.65 (1.50-1.81) | .000 | 1.00 (0.81-1.23) | .970 |
| Level of independence domaine | 14.5 (1.9) | 1.42 (1.29-1.56) | .080 | ... | 1.10 (0.98-1.24) | .103 | ... | ||
| Social relationships domaine | 13.4 (2.6) | 1.52 (1.37-1.69) | .000 | 1.14 (1.00-1.30) | .048 | 1.65 (1.49-1.83) | .000 | 1.05 (0.89-1.24) | .549 |
| Environment domaine | 13.9 (2.6) | 1.76 (1.56-2.00) | .000 | 1.56 (1.28-1.89) | .000 | 2.46 (2.11-2.87) | .000 | 2.21 (1.71-2.86) | .000 |
| Spirituality/religion/personal beliefs domaine | 15.3 (2.9) | 1.17 (1.08-1.27) | .000 | 0.76 (0.63-0.91) | .003 | 1.40 (1.29-1.51) | .000 | 1.06 (0.89-1.28) | .507 |
| Depression score (higher score = more depressed) | 17.3 (3.3) | 0.78 (0.72-0.84) | .000 | 0.88 (0.80-0.96) | .006 | 0.63 (0.58-0.69) | .000 | 0.71 (0.62-0.80) | .000 |
| ART regimen | |||||||||
| 3TC, d4T + Efavirenz | 411 (79.2) | 1.00 | 1.00 | 1.00 | 1.00 | ||||
| 3TC, d4T + Nevirapine | 108 (20.8) | 4.08 (1.73-9.63) | .001 | 2.16 (0.80-5.87) | .130 | 5.25 (2.57-10.72) | .000 | 4.61 (1.48-14.34) | .008 |
aUsing block entry;bHosmer and Lemeshow Chi-square = 11.67, df = 8, p = .166; bCox & Snell R2 .26; b Nagelkerke R2 .42;
cHosmer and Lemeshow Chisquare = 25.05, df = 8, p.002; cCox & Snell R2 .54; c Nagelkerke R2 .76
d Mean scores range from 1 to 5, with 5 indicating the highest, most positive perceptions of quality of life or general health perceptions.
e Overall domain scores range from 4 to 20, with 20 indicating the highest, most positive perceptions.