Figure 3.

Norepinephrine and KCl activate different populations of hippocampal precursors. A, Culturing adult hippocampal cells in the presence of NE and KCl resulted in over a 4.5-fold increase in neurosphere numbers compared with a twofold increase in the number of neurospheres observed in the presence of either norepinephrine or KCl alone (mean ± SEM; *p < 0.05). B, Distribution of neurospheres according to size showing approximately a fivefold increase in the number of large neurospheres, measuring >200 μm, obtained in the presence of NE+KCl (mean ± SEM; *p < 0.05, **p < 0.01).