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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Cell Biochem Funct. 2009 Jul;27(5):296–308. doi: 10.1002/cbf.1573

Figure 8. Purified colipase increased lipid-dependent cytotoxicity mediated by PTL but was without effect on the cytotoxic activity CTLs induced with a standard lot of IL-4.

Figure 8

The CTLs were induced for 5 days with lot E031047 IL-4 and expressed PLRP2 mRNA (not illustrated). CTLs or the lipase PTL were combined with or without colipase and tested in 48 hour tumor viability assays in the presence or absence of trilinolein. Tumor viability was unchanged by the addition of colipase to CTLs incubated in the presence of lipid when compared to assays lacking lipids. In assays containing PTL, tumor viability was significantly reduced upon addition of colipase when lipid was present.