TABLE 1.

Serum antibody responses to recombinant M. tuberculosis 38-kDa, rMTB48, and rCFP-10/ESAT-6 antigens

Group and status	No. of subjects	Serum antibody response to antigena (OD492 [mean ±SD])
		r38kDb	rMTB48	rCFP-10/ESAT-6
Healthy controls
PPD−	129	0.064 ± 0.04	0.052 ± 0.03	0.040 ± 0.03
PPD+	131	0.082 ± 0.07c	0.077 ± 0.06c	0.049 ± 0.05
Total	260	0.073 ± 0.06	0.064 ± 0.05	0.044 ± 0.04
TB patients
Bacterium−	131	0.177 ± 0.13d	0.150 ± 0.16d	0.119 ± 0.16d
Bacterium+	119	0.254 ± 0.26e	0.241 ± 0.29e	0.226 ± 0.39e
Total	250	0.213 ± 0.20f	0.193 ± 0.23f	0.170 ± 0.30f

^aSerum antibody responses to recombinant M. tuberculosis 38-kDa, rMTB48, and rCFP-10/ESAT-6 antigens were measured by determining the optical density at 492 nm (OD₄₉₂).

^br38kD, recombinant 38-kDa antigen.

^cP < 0.05 versus the PPD⁻ healthy subjects.

^dP < 0.001 versus healthy controls.

^eP < 0.05 versus bacterium-negative TB patients.

^fP < 0.001 versus healthy controls.