TABLE 4.
Comparison of postimmunization Hib, meningococcus group C, and tetanus responses from this study with those of a study administering the same DTaP5/IPV/Hib-TT and MCC vaccines but no pneumococcal vaccine
| Study | Anti-PRP IgG |
Anti-meningococcus group C IgG capsular polysaccharide (SBA) |
Antitetanus IgG |
|||
|---|---|---|---|---|---|---|
| GMC (μg/ml) | % with concn ≥0.15 μg/ml | GMT (μg/ml) | % with titer ≥1:8 | GMC (EU/mlc) | % with concn ≥0.01 EU/ml | |
| Kitchin et al. (11)a | 2.17 (1.34, 3.53)b | 87.8 | 2,165 (1,517, 3,089) | 100 | 1.30 (1.00, 1.68) | 100 |
| This study | 0.77 (0.51, 1.16) | 84.6 | 377 (281, 505) | 98.1 | 0.53 (0.44, 0.65) | 100 |
a
The results are for the group receiving MCC-CRM197 only.
b
Values in parentheses are 95% CIs.
c
EU/ml, endotoxin units per milliliter.