TABLE 3.
Estimation of protective levels of serum anti-Vi IgG before and after vaccination with Vi polysaccharide vaccinea
| Day | No. of total participants | No. of participants with: |
% with protective anti-Vi IgG level (≥1 μg/ml) | |
|---|---|---|---|---|
| <1 μg/ml anti-Vi IgG | >1 μg/ml anti-Vi IgG | |||
| 0 | 996 | 549 | 447 | 44.9 |
| 28 | 996 | 23 | 973 | 97.7 |
a
The Vi bead assay was used to measure serum anti-Vi IgG at day 0 (before vaccination) and 28 days after vaccination with the Vi polysaccharide vaccine. By comparing the anti-Vi IgG RLU to the total IgG standard curve, we estimated the number of participants with protective (i.e., 1 μg/ml) levels of serum anti-Vi IgG before and after vaccination.