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Screen summary for cytotoxic ExoU-LINKER molecules without supernatant phospholipase activity
| Designation | Sequence | Membrane retention (OD570) |
|---|---|---|
| Vector | NA | 1.3 |
| WT ExoU | NA | 0.275 |
| L104 | TSCLN | 0.332 |
| K161 | CLNIK | 0.373 |
| I254 | CLNTI | 0.301 |
| P365 | LLFKQ | 0.279 |
| A393 | CLNSA | 0.452 |
| N443 | FTCLN | 0.453 |
| A452 | HLLFK | 0.544 |
| L537 | VFKQL | 0.425 |
| W560 | CLNTW | 0.111 |
| D572 | HQCLN | 0.122 |
| D572* | CLNID | 0.123 |
| L618 | CLNTL | 0.302 |
| L651 | MFKQL | 0.426 |
