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. 2010 Jan 13;84(7):3189–3200. doi: 10.1128/JVI.01964-09

FIG. 3.

FIG. 3.

Comparison of the unliganded Ad11, Ad21, and Ad35 knob structures. (A) Alignment of the Ad21, Ad35, and Ad11 knob sequences performed with ClustalW2. The positions of β-strands are indicated above the alignment with arrows. (B) Superposition of the unliganded Ad21, Ad35, and Ad11 knobs showing the surface-exposed HI, DG, GH and IJ loops. The Ad21 knob is green, the Ad35 knob is ruby, and the Ad11 knob is gray. (C) Close-up views of the Ad21 DG and HI loops (left) and the Ad21 GH and IJ loops (right). (D) Close-up view of the corresponding regions in the Ad35 knob. (E) Close-up view of the corresponding regions in the Ad11 knob. The Ad21 knob, Ad35 knob, and Ad11 knob loops are colored as described above (B). Hydrogen bonds are represented with dashed lines.