TABLE 2.
Selection analysis of the VP1 gene for various EV-71 subgenogroups
| Subgenogroup | Mean dN/dS (CI)a | Positive selection site datab |
||
|---|---|---|---|---|
| Position | Normalized dN − dS | P value | ||
| B1 | 0.036 (0.025-0.049) | NA | ||
| B2 | 0.063 (0.046-0.084) | 145 | 19.849 | 0.0078 |
| B3 | 0.172 (0.128-0.226) | 145 | 38.285 | 0.0112 |
| 237 | 23.138 | 0.0899 | ||
| B4 | 0.075 (0.059-0.094) | 98 | 3.616 | 0.0706 |
| 145 | 16.695 | <0.0001 | ||
| 241 | 4.260 | 0.0146 | ||
| B5 | 0.050 (0.023-0.093) | NA | ||
| C1 | 0.039 (0.031-0.048) | 98 | 2.980 | 0.0282 |
| 145 | 3.264 | 0.0248 | ||
| C2 | 0.054 (0.039-0.072) | 241 | 3.247 | 0.0979 |
| C3 | 0.074 (0.023-0.171) | NA | ||
| C4 | 0.029 (0.021-0.040) | NA | ||
| C5 | 0.047 (0.020-0.091) | NA | ||
a
CI, 95% confidence interval.
b
NA, not applicable.