FIG. 1.
Characterization of highly purified HHPV-1 virions. (A) Analyses of the purification in equilibrium centrifugation by A260 (•), CsCl gradient density (○), and infectivity (░⃞) of the gradient fractions. (B) Protein profiles of the gradient fractions in 14% Tricine-SDS-PAGE. Molecular masses of the standard proteins (in kilodaltons) are shown on the left. (C) TLC of the fractions showing phosphatidylglycerol (PG). The numbers of the gradient fractions for panels A to C are shown in panel C. P, pellet. (D) Negative-stained electron micrograph of 2×-purified HHPV-1. Sample was stained with 1% (wt/vol) ammonium molybdate (pH 7.0). Bar, 100 nm.