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Immunogenicity of wild-type and disulfide-bond-variant gp120s. (a) The mean total proliferation in response to 45 peptides was reduced for mice immunized with gp120dss298 or gp120dss378. (b) The mean number of stimulatory peptides (SI > 2) was reduced for mice immunized with gp120dss298 or gp120dss385. *, P < 0.05; **, P < 0.005.
