FIG. 5.

Cross-clade serum microneutralization in mice immunized orally with inactivated or live recombinant baculovirus at a log₂ HA titer of 8 with or without 10 μg rCTB. Viruses from clade 1.0 (A/Vietnam/1203/2004), clade 2.1 (A/Indonesia/CDC1031/2007), clade 2.3 (A/chicken/Nongkhai/NIAH400802/2007), and clade 8.0 (A/chicken/Henan/12/2004) were used for this study. Sera from the day of peak response, day 21 after the final immunization, were used for the assay. Each point represents the arithmetic mean value (n = 6) ± standard error (*, P < 0.05; **, P < 0.02; ***, P < 0.001).