Skip to main content
. Author manuscript; available in PMC: 2010 Oct 30.
Published in final edited form as: Chem Biol Interact. 2009 Jul 15;181(3):447–454. doi: 10.1016/j.cbi.2009.07.003

Fig 3.

Fig 3

Effect of 6 or 12 hours of exposure to 6-formylindolo[3,2-b]carbazole (FICZ) on CYP1A expression in dechorinated 48-hpf zebrafish embryos. Embryos were exposed to 10 nM FICZ (hatched bars) and 100 ppm DMSO, or 100 ppm DMSO only (Ctrl; filled bars) for 6 or 12 hours. Relative level of CYP1A gene expression was calculated by EΔCt[sample]/mean EΔCt[control]. Significant statistical differences between groups (n=4) were determined using one-way ANOVA followed by Bonferroni’s Multiple Comparison Test of selected pairs (post hoc test) with log transformed data. Differences between the FICZ-exposed groups and the corresponding controls and between the groups exposed to FICZ for 6 or 12 hours are shown by stars (*** = p < 0.001) and different letters (p < 0.01), respectively.