Table 1.
Group | N | Age |
Sex |
Patient CDR box score |
|||
---|---|---|---|---|---|---|---|
mean (SD) |
adj mean (SE) |
F/M |
adj meana (SE) |
||||
Caregiver | Patient | Couple | Caregiver | Patient | |||
FTD couples | 15 | 56.90 (7.60) | 60.37 (6.09) | 58.64 (1.53) | 13/2 | 2/13 | 6.93 (0.51) |
AD couples | 16 | 54.02 (7.03) | 59.28 (5.28) | 56.65 (1.48) | 10/6 | 6/10 | 4.56g** (0.50) |
Control couplesb | 21 | 64.03 (6.60) | 66.58 (7.88) | 65.30c***,d** (1.30) | 15/6 | 6/15 | −0.09f*** (0.45) |
adj mean (SE) | |||||||
Total | 52 | 58.31 (0.99) | 62.08e*** (0.93) | 60.19 (0.83) | 38/14 | 14/38 | 3.80 (0.27) |
FTD = frontotemporal dementia; AD = Alzheimer’s disease; SD = standard deviation; adj = adjusted; SE = standard error; F = female; M = male; CDR = Clinical Dementia Rating Scale.
Corrected for patient age.
For controls, the “patient” was the member of the couple who participated in the larger study being conducted through the UCSF MAC and UC Berkeley, as a patient analog; the “caregiver” was the member of the couple who participated in a subset of study tasks, as a caregiver analog. Unless otherwise noted, analyses reporting on “patients” include control patient analogs and analyses reporting on “caregivers” include control caregiver analogs.
Control couples > AD couples
Control couples > FTD couples
Patients > caregivers
Controls < FTD & AD
AD < FTD
p < .01,
p < .001