Table 2.
Comparison of Remitters vs Non-Remitters
| Non-remitter (N=118) | Remitter (N=72) | p-value | |
|---|---|---|---|
| White race, n (%) (n=190) | 109 (92.4%) | 64 (88.9%) | 0.44 |
| Sex, male, n (%) (n=190) | 52 (44.1%) | 31 (43.1%) | 1.00 |
| Late age of onset, n (%) (n=181) | 51 (45.5%) | 32 (46.4%) | 1.00 |
| Age, mean (SD) (n=190) | 69.2 (7.7) | 67.6 (6.7) | 0.21 |
| Age of onset, mean (SD) (n=181) | 53.5 (17.9) | 53.7 (16.6) | 0.93 |
| Education, mean (SD) (n=190) | 14.2 (2.9) | 14.7 (3.4) | 0.19 |
| MMSE, mean (SD) (n=189) | 27.6 (1.9) | 28.0 (2.1) | 0.06 |
| VRF, mean (SD) (n=188) | 12.3 (4.5) | 10.6 (4.6) | 0.01 |
| Baseline MADRS, mean (SD) (n=190) | 26.6 (4.5) | 25.2 (4.1) | 0.06 |
| Episodic Memory, mean (SD) (n=180) | -0.82 (3.2) | 0.37 (3.1) | 0.005 |
| Language Processing, mean (SD) (n=175) | -0.50 (2.5) | 0.47 (2.1) | 0.004 |
| Working Memory, mean (SD) (n=179) | -0.09 (2.3) | 0.20 (2.2) | 0.42 |
| Processing Speed, mean (SD) (n=174) | -0.56 (2.8) | 0.74 (1.9) | 0.0001 |
| Executive Function, mean (SD) (n=167) | -0.58 (3.4) | 0.61 (3.2) | 0.02 |
| Total Fazekas Score, mean (SD) (n=174) | 4.4 (2.5) | 3.8 (2.1) | 0.09 |
| Categorical Fazekas (Total Fazekas >2), n (%) (n=174) | 76 (72.4%) | 43 (62.3%) | 0.18 |
| Last Sertraline Dose (mg), mean (SD) (n=186) | 125.7 (56.9) | 105.9 (46.6) | 0.02 |
Note: Fisher's exact test for categorical variables and Wilcoxon Rank-Sum test for continuous variables