FIGURE 3.

Decylubiquinone attenuates myxothiazol-induced reduction in oxygen consumption rates in synaptosomes. Rat brain synaptosomes were incubated with a series of concentrations of myxothiazol (0–1 μm) in the absence (■) and presence (□) of 50 μm decylubiquinone in Krebs buffer at 37 °C, and rates of oxygen consumption were recorded and plotted against myxothiazol concentrations. Experiments were performed on at least three individual preparations, and results are expressed as mean ± S.E. (error bars). Significant differences between the decylubiquinone-treated and untreated samples are shown by ** for p < 0.01 and *** for p < 0.001.