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Prion transmission to Tg(HuPrP)Prnpo/o mice
| Case No. | Codon 129 | Tg(HuPrP-129V) |
Tg(HuPrP-129M) |
||
|---|---|---|---|---|---|
| ni/nsa | IPb | ni/ns | IP | ||
| days | days | ||||
| 1 | MM | 6/6 | 294 ± 11 | 6/6 | 201 ± 16 |
| 2 | MM | 5/5 | 198 ± 2 | 5/5 | 130 ± 12 |
| 3 | MM | 5/5 | 240 ± 1 | 5/5 | 160 ± 6 |
| 4 | MM | 5/5 | 230 ± 15 | 6/6 | 162 ± 4 |
| 5 | VV | 5/5 | 226 ± 5 | 5/6 | 434 ± 7 |
| 6 | VV | 7/7 | 266 ± 2 | 7/8 | 396 ± 17 |
| 7 | VV | 7/7 | 190 ± 4 | 8/9 | 392 ± 21 |
| 8 | VV | 6/6 | 232 ± 6 | 5/7 | 417 ± 12 |
a ns, number sick; ni, number of mice inoculated.
b IP, incubation period.
