FIGURE 6.

Relationship between EC₅₀ values and cis-trans preferences for Pro and analogues at position 136. All values are relative to Pro. Solid line and open circles, Pro, Aze, and Pip using cis-trans values determined in the present study for the Gly-Phe-Xaa-Gly sequence (Table 3). Dashed line and open diamonds, Pro, Aze, and Pip using cis-trans values previously determined for sequences that do not have an aromatic N-terminal to the Pro analogue. Solid squares, data points (flp, Mor, and 3-Me-Pro) that deviate from the trend set by the solid line.