TABLE 1.
Identities between human (h) and dmOCA-S components (a subset), Oct-1 and Pdm-1 POU domains, and histone promoter octamer motifs
Peptide sequence identities were based upon pairwise alignment using the Smith-Waterman algorithm. GenBankTM accession numbers are: p38/GAPDH (CAA25833.1), p36/LDH-A (NP_005557.1), p36/LDH-B (CAA68701.1), Nm23-H1 (AA085436.1), Nm23-H2 (CAB37870.1), Oct-1 (AAM77920.1), dmGapdh-1 (NP_525108.2), dmGapdh-2 (NP_542445.1), dmLdh (AAB07594.1), Awd (NP_476761.2), Pdm-1 (AAA28829.1). Comparison between Pdm-1 and Oct-1 is limited to the POU domains with the POU-specific (POUS) and POU-homeo (POUH) subdomains. Underlined are the octamer nucleotides, of the dmH2B and dmH4 promoters, which are deviated from the canonical hH2B octamer site.
