Table 2.
Baseline co-morbidity in PsA cases and seronegative RA control cohorts at baseline
| Co-morbid disorders | Control (n = 1115), n (%) | All PsA cohort (n = 596) |
|
|---|---|---|---|
| n (%) | Adjusted ORa (95% CI) | ||
| Cardiovascular disorders | |||
| Hypertension | 377 (34) | 174 (29) | 0.96 (0.87, 1.07) |
| Angina | 93 (8) | 9 (2) | 0.72 (0.47, 1.11) |
| Myocardial infarction | 50 (4) | 6 (1) | 0.64 (0.34, 1.20) |
| Stroke | 38 (3) | 13 (2) | 0.79 (0.56, 1.11) |
| Pulmonary disorders | |||
| Bronchitis and emphysema | 13 (1) | 6 (1) | 1.07 (0.59, 1.93) |
| Asthma* | 167 (15) | 51 (9) | 0.80 (0.65, 0.98) |
| COPD | 98 (9) | 26 (4) | 0.96 (0.75, 1.22) |
| Endocrine disorders | |||
| Diabetes | 81 (7) | 32 (5) | 0.97 (0.74, 1.26) |
| Hyperthyroidism | 44 (4) | 8 (1) | 0.82 (0.53, 1.26) |
| GIT disorders | |||
| Peptic ulcer disease | 75 (7) | 41 (6.88) | 1.19 (0.97, 1.46) |
| Liver disease | 23 (2) | 28 (4.70) | 1.20 (0.91, 1.56) |
| Renal disease | 31 (3) | 12 (2.01) | 0.91 (0.59, 1.40) |
| CNS disorders | |||
| Demyelination | 7 (1) | 0 (0) | – |
| Epilepsy | 18 (2) | 15 (3) | 1.02 (0.70, 1.49) |
| Depression | 195 (17) | 114 (19) | 1.08 (0.94, 1.23) |
| Past malignancy | 71 (6) | 13 (2) | 0.70 (0.45, 1.06) |
aORs are calculated versus control and adjusted for age, sex and smoking.
*P < 0.05. COPD: chronic obstructive pulmonary disease.