Table I. Number Of Mice With Luciferase Positive Lungs Or Lymph Nodes (Ln) At Sacrifice As Judged By Ex Vivo Optical Imaging.

Degree of involvement	LAPC-4	LAPC-9
Lungs
No metastasis	1	6
1–2 Positive lobes	2	0
3–4 Positive lobes	1	1
All lung lobes positive	5	0
Incidence of lung metastasis	89%	14%
Lymph nodes
No metastasis	6	6
Positive brachial LNs	2	1
Positive cervical LNs	3	0
Incidence of LN metastasis	33%	14%

In the LAPC-4 implanted mice 2 out of 9 mice had both brachial and cervical lymph node metastases. The total number of animals with luciferase positive lymph nodes in the LAPC-4 group was 3 animals.