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. Author manuscript; available in PMC: 2010 Mar 15.
Published in final edited form as: Eur J Immunol. 2008 May;38(5):1194–1203. doi: 10.1002/eji.200737882

Figure 7.

Figure 7

Spliced XBP-1 enhances IFN-β induction. XBP-1−/− MEFs (A) and RAW264.7 macrophages (B) were transfected with XBP-1s (ν) or vector control (■). At 24 h post transfection, MEFs were treated as in Figure 6. RAW264.7 cells were pretreated with 1 μM Tpg for 1 h then LPS for 3 h. IFN-β mRNA expression is shown normalized to GAPDH. Results shown are mean ±SD and are representative of 3 independent experiments. Asterisks (*) indicate p<0.05 for combined experiments comparing control vs. XBP-1s for the conditions indicated.