Table 3.
COMPASS_Change Scores for patients with MSA and PD at 1-year follow-up.
| COMPASS_Change Domains | DX | N | Mean | Std. Dev. | P-Value* |
|---|---|---|---|---|---|
| Orthostatic Intolerance | MSA PD |
21 18 |
29.52 10.50 |
19.14 19.16 |
0.003 |
| Upper Gastrointestinal Symptoms | MSA PD |
21 18 |
1.52 0.22 |
1.99 2.46 |
0.038 |
| Bladder Dysfunction | MSA PD |
21 18 |
8.81 2.50 |
13.68 5.22 |
0.133 |
| Vasomotor Symptoms | MSA PD |
21 18 |
2.14 −0.56 |
2.54 2.36 |
0.001 |
| Diarrhea | MSA PD |
21 18 |
0.95 0.28 |
4.64 1.18 |
0.674 |
| Constipation | MSA PD |
21 18 |
1.43 1.11 |
4.78 2.74 |
0.575 |
| Pupillomotor Symptoms | MSA PD |
21 18 |
2.29 1.67 |
2.78 2.40 |
0.415 |
| Sleep Dysfunction | MSA PD |
21 18 |
2.50 0.28 |
8.25 3.31 |
0.216 |
| Secretomotor Dysfunction | MSA PD |
21 18 |
6.81 5.00 |
8.45 5.99 |
0.760 |
| Sexual Failure (men only) | MSA PD |
11 10 |
1.82 2.00 |
3.37 3.50 |
0.918 |
| COMPASS_Change (max score 200) | MSA PD |
21 18 |
56.93 22.11 |
45.92 32.79 |
<0.001 |
| COMPASS_Change_Select (5 domains) | MSA PD |
21 18 |
49.79 17.72 |
37.84 26.45 |
<0.001 |
*
Based on Wilcoxon sign rank sum test.