. Author manuscript; available in PMC: 2010 Dec 16.

Published in final edited form as: JAMA. 2009 Dec 16;302(23):2565–2572. doi: 10.1001/jama.2009.1836

Table 4.

Association of sex-standardized log-leptin with incident all-cause dementia and incident Alzheimer’s disease, adjusted for age and sex only, stratified by sex-specific quartiles of Waist Hip Ratio and by obese (BMI ≥30 kg/m²) or non-obese status.

	All-cause Dementia			Alzheimer’s Disease

	Hazard Ratio			Hazard Ratio
Model	Cases/N	(95% CI)	P	Cases/N	(95% CI)	P
Q1–Q3 Waist Hip Ratio	79/586	0.57 [0.45–0.73]	<0.001	70/586	0.53 [0.41–0.69]	<0.001
Q4 Waist Hip Ratio	31/195	0.92 [0.60–1.40]	0.685	19/195	0.77 [0.45–1.32]	0.337
BMI < 30 kg/m²	95/561	0.69 [0.55–0.87]	0.002	79/561	0.63 [0.49–0.81]	0.001
BMI ≥30 kg/m²	16/221	1.87 [0.86–4.06]	0.113	10/221	0.74 [0.28–1.97]	0.547

Hazard ratios are per one-SD increment in sex-standardized log-leptin.