Table 1.

Model parameters determined from published data

Parameter	Value	Description
ρF	9.44 kcal/g	Energy density of F
ρP	4.7 kcal/g	Energy density of P
ρG	4.18 kcal/g	Energy density of G
ρK	4.45 kcal/g	Energy density of ketones
hP	1.6 g H2O/g	P hydration coefficient
hG	2.7 g H2O/g	G hydration coefficient
ηF	0.18 kcal/g	F synthesis cost
ηP	0.86 kcal/g	P synthesis cost
εP	0.17 kcal/g	P degradation cost
ηG	0.21 kcal/g	G synthesis cost
ηN	5.4 kcal/g	Urea synthesis cost/g nitrogen
εd	0.835	DNL efficiency
εg	0.8	GNG efficiency
εk	0.81	KTG efficiency
αF	0.025	TEF factor for FI
αC	0.075	TEF factor for CI
αP	0.25	TEF factor for PI
γF	4.5 kcal•kg−1•day−1	Specific RMR for adipose
γ̂FFM	19 kcal•kg−1•day−1	Basal specific RMR for FFM
ξBW	0.16	ECF response to BW changes
ξCI	4000 mg/day	ECF response to CI changes
ξNa	3 mg•ml−1•day−1	ECF response to sodium changes
τBW	1,000 days	ECF response time for BW changes
τT	7 days	Response time for T changes
D̂g	180 g/day	Baseline glycogenolysis rate
KDNL	2	Glycogen constant for DNL
d	4	Hill coefficient for DNL
D̂F	140 g/day	Baseline lipolysis rate
AL	3.8	Maximum lipolysis change
BL	0.9	Minimum lipolysis change
τL	1.44 days	Response time for lipolysis
KL	4	Body fat constant for lipolysis
SL	2	Hill coefficient for lipolysis
ψ	0.4	PA effect on lipolysis
AK	0.8	Maximum KTG fraction
kP	0.69	Effect of PI on KTG
kG	0.69	Effect of G on KTG
KK	1	Sets basal KTG rate
KTGthresh	70 g/day	Renal threshold KTG rate
KUmax	20 g/day	Maximum ketone excretion
KTGmax	400 g/day	Maximum KTG
D̂P	300 g/day	Baseline proteolysis rate
χ	0	Effect of PI on protein turnover
GN̂GP	300 kcal/day	Basal GNGP rate
ΓC	0.39	Effect of CI on GNGP
ΓP	0.32	Effect of PI on GNGP
τPI	1.1 days	Response time of ProtOx to PI changes

See Glossary of Model Variables for definitions of the abbreviations.